Invited Talks

"Enabling Materials for Microphysiological Systems" Microphysiological Systems Seminar @ University of Tübingen (09/2023)

"Engineering the Cellular Microenvironment." Micro- and Nanosystems Seminar @ Tampere University (08/2023)

"Enabling Materials for Microphysiological Systems: from Microfluidics to Hydrogels." Cell Biology Seminar @ HZI Braunschweig, Germany (08/2023).

"Microfabrication of Organs-on-Chips", EUROoCS Academy @ MPS World Summit, Berlin, Germany (06/2023).

"Enabling Materials for Brains-on-Chips: from Microfluidics to Hydrogels", Brains on Chips Symposium, Braunschweig, Germany (05/2023).

"Bio/Microsystems Engineering to Facilitate Management and Biomolecular Understanding of Neuropsychiatric Disorders", Biomedical Systems Seminar @ University of Stuttgart, Germany (10/2022).

"On-chip technology towards improved care and understanding of neuropsychiatric disorders.", IMTEK Seminar @ University of Freiburg, Germany (05/2022).

"Microfluidics beyond Glass and PDMS: Examples from the Realm of Organs-on-Chips.", Biophysics Seminar @ OvGU Magdeburg, Germany (05/2022).

"Bio-Microengineered Cellular Systems towards a better Understanding of Neuropsychiatric Disorders". CCB/CBI Seminar @ TU Dortmund, Germany (03/2022).

"Addressing Neuropsychiatric Disorders using Bio-Microengineered Interfaces." Electrical Engineering Seminar @ RWTH Aachen & FZ Jülich, Germany (06/2021).

"It started in Linz - A 20,000-mile academic journey" & "Organs-on-Chips: the better lab rats?" LIT Focus Lecture @ JKU Linz, Linz, Austria (05/2021).

"Organs-on-Chips: An Engineer's Primer." Seminar @ Spiber Technologies, Stockholm, Sweden (05/2021).

"Tape-based barrier-on-chip for small intestine modeling." Seidler Research Group Seminar @ Hannover Medical School, Germany (04/2021).

"Addressing Neuropsychiatric Disorders using Microsystems Engineering." Human & Biotechnology Seminar @ TU Graz, Austria (11/2020).

"Next-generation Microphysiological Systems to recapitulate Human Physiology in-vitro." New Updates in Drug Formulation & Bioavailability, Copenhagen, Denmark (09/2020).

"Beyond PDMS: New Integration Strategies for Barrier-on-Chip Systems." international MicroNanoConference (iMNC), Utrecht, The Netherlands (12/2019).

"Study of nitrosative stress in a hiPSC-derived neurovascular unit-on-chip (as an example of challenges and opportunities in microphysiological models of biological barriers)." Biomedical Engineering and Physics Seminar @ Amsterdam Medical Center, The Netherlands (12/2019).

Presentations

(presenting author underlined if different from first author)

T.E. Winkler, I. Matthiesen, F. Buck, J. Bugter, D. Voulgaris, P. Nikolakopoulou, and A. Herland. "Modeling Nitrosative Stress and Antioxidant Prophylaxis using an On-Chip Isogenic Blood-Brain Barrier." Stem Cells for Disease Modeling and Regeneration. Tübingen, Germany (06/2022). Oral Presentation.

T.E. Winkler and A. Herland. "Non-specific Sorption of Small Molecules in Organ-on-Chip Systems." European Organ-on-Chip Conference (EUROoC). Virtual conference due to COVID-19 (07/2021). Select Oral Presentation (Top-8 abstract).

T.E. Winkler, I. Matthiesen, D. Voulgaris, P. Nikolakopoulou, and A. Herland. "Continuous Monitoring of Isogenic Blood-Brain Barrier Integrity in a PDMS-Free Microphysiological System." International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS). Poster-only virtual conference due to COVID-19 (10/2020).

T.E. Winkler, M. Feil, E.F.G.J. Stronkman, I. Matthiesen, and A. Herland. "A tape-based microphysiological model of the small intestine." European Organ-on-Chip Conference (EUROoC). Virtual conference due to COVID-19 (07/2020). Poster presentation.

T.E. Winkler, I. Matthiesen, D. Voulgaris, L. Delsing, A. Lundin, P. Nikolakopoulou, and A. Herland. "Continuous barrier integrity monitoring in a microphysiological hiPSC model of the BBB." European Organ-on-Chip Conference (EUROoC), Graz, Austria (07/2019). Select Oral presentation. Best Paper/Presentation.

T.E. Winkler, I. Matthiesen, D. Voulgaris, P. Nikolakopoulou, and A. Herland. "Bioelectronics for Next-Generation Neurovascular Unit Organs-on-Chips" Bioelectronics Gordon Research Conference (GRC), Andover, New Hampshire (06/2019). Poster presentation.

I. Matthiesen, T.E. Winkler, D. Voulgaris, P. Nikolakopoulou, and A. Herland. "Modeling of the human blood brain barrier (BBB) in stroke." Nordic Organ on a Chip Symposium, Oslo, Norway (02/2019). Poster presentation.

T.E. Winkler, E. Kim, M. Kang, G.F. Payne, D.L. Kelly, and R. Ghodssi. "Systems Integration of Cellular and Molecular Sensing towards Point-of-Care Treatment Monitoring in Schizophrenia." International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS), Savannah, Georgia (10/2017). Oral presentation.

A. Herland, T.E. Winkler, D. Voulgaris, B.M. Maoz, K.K. Parker, and D.E. Ingber. "Metabolic coupling between the endothelium and neurons in the neurovascular unit revealed using human organs-on-a-chips." Joint EMBEC/NBC Conference on Biomedical Engineering and Medical Physics, Tampere, Finland (06/2017). Oral presentation.

T.E. Winkler, S.L. Brady, E. Kim, H. Ben-Yoav, D.L. Kelly, G.F. Payne, and R. Ghodssi. "Molecular Processes in an Electrochemical Clozapine Sensor." American Vacuum Society (AVS) International Symposium, Nashville, Tennessee (11/2016). Oral Presentation.

T.E. Winkler, F. Zang, F.O. Stevenson, J.N. Culver, and R. Ghodssi. "Portable Immunoassay for Label-free Antibody Detection in Whole Blood." International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS), Dublin, Ireland (10/2016). Poster presentation.

T.E. Winkler, H. Ben-Yoav, D.L. Kelly, and R. Ghodssi. "Osmotic Erythrocyte Lysis for Chemical- and Label-free Impedance Cytometry." International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers), Anchorage, Alaska (06/2015). Proceedings published. Oral presentation.

T.E. Winkler, H. Ben-Yoav, D.L. Kelly, and R. Ghodssi. "Flow Focusing for Microfluidic Impedance Cytometry." BMES/FDA Frontiers in Medical Devices Conference, College Park, Maryland (05/2015). Poster presentation.

T.E. Winkler, H. Ben-Yoav, S.E. Chocron, E. Kim, G.F. Payne, D.L. Kelly, and R. Ghodssi. "Microsystems for Brain Health." IEEE EMBS BRAIN Grand Challenges Conference, Washington, District of Columbia (11/2014). Poster presentation.

T.E. Winkler, H. Ben-Yoav, D.L. Kelly, and R. Ghodssi. "Microsystem for Particle Counting and Sizing with Tunable Sensitivity and Throughput." Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head, South Carolina (06/2014). Proceedings published. Poster presentation.

T.E. Winkler, H. Ben-Yoav, S.E. Chocron, E. Kim, D.L. Kelly, G.F. Payne, and R. Ghodssi. "Electrochemical interference in a catechol-modified chitosan redox cycling amplification system for clozapine detection." Electrochemical Society (ECS) Meeting, San Francisco, California (10/2013). Oral presentation.

H. Ben-Yoav, T.E. Winkler, E. Kim, D.L. Kelly, G.F. Payne, and R. Ghodssi. "Catechol-modified chitosan system as a bio-amplifier for schizophrenia treatment analysis." Materials Research Society (MRS) Spring Meeting, San Francisco, California (04/2013). Proceedings published. Oral presentation.

T.E. Winkler, P.R. Stone, T. Li, R. Jakieła, K.M. Yu, A. Bonanni, and O.D. Dubon. "Effects of compensation in Ga1−xMnxP." IEEE International Magnetics Conference (Intermag), Taipei, Taiwan (04/2011). Oral presentation.

Contributions as Co-Author

(presenting author underlined if different from first author)

J. Bugter, F. Buck, S. Fuchs, T. Mayr, and T.E. Winkler. "Overcoming oxygen impermeability in PDMS-free organ-on-a-chip devices with nanoporous plastics." Joint Microphysiological Systems (MPS) World Summit & European Organ-on-Chip Society (EUROoCS) Conference. Berlin, Germany (06/2023). Poster Presentation.

J. Bugter, F. Buck, E. Hedberg, A. Herland, and T.E. Winkler. "Gap Junction-mediated Cell-cell Communication through Ultra-thin, Ultra-porous Barrier-chip Membranes." European Organ-on-Chip Society (EUROoCS) Conference. Grenoble, France (07/2022). Poster Presentation.

I. Matthiesen, D. Voulgaris, P. Nikolakopoulou, T.E. Winkler, and A. Herland. "Continuous Monitoring shows Protective Effects of Antioxidant on Blood-Brain Barrier µ-Fluidic Model." NanoBioTech, Montreux, Switzerland (11/2021). Poster Presentation.

E. Hedberg, T.E. Winkler, I. Matthiesen, D. Voulgaris, P. Nikolakopoulou, and A. Herland. "Ultra-thin, ultra-porous membranes using femtosecond laser photoablation." European Organ-on-Chip Society (EUROoCS) Conference. Virtual conference due to COVID-19 (07/2020).

P. Nikolakopoulou, D. Voulgaris, I. Matthiesen, T.E. Winkler, and A. Herland. "The diabetic brain: an on-chip approach." European Organ-on-Chip Conference (EUROoC). Virtual conference due to COVID-19 (07/2020).

I. Matthiesen, T.E. Winkler, D. Voulgaris, P. Nikolakopoulou, A. Lundin, and A. Herland. "Real-time monitoring of the human blood-brain barrier modeled on a microfluidic chip." Neuroscience, Chicago, Illinois (10/2019). Poster Presentation.

P. Nikolakopoulou, D. Voulgaris, I. Matthiesen, T.E. Winkler, and A. Herland. "Microglia mediated neuroinflammation and endogenous regeneration. Are they connected?" Neuroscience, Chicago, Illinois (10/2019). Poster Presentation.

D. Voulgaris, P. Nikolakopoulou, I. Matthiesen, T.E. Winkler, and A. Herland. "When the human body attacks itself: A Blood-Brain-Barrier-on-a-chip study." European Organ-on-Chip Society (EUROoCS) Conference, Graz, Austria (07/2019). Poster presentation. Top Poster Award.

I. Matthiesen, M. Jury, C. Aronsson, P. Nikolakopoulou, T.E. Winkler, D. Voulgaris, R. Selegård, D. Aili, and A. Herland. "Brain extracellular matrix mimicking hydrogels for modeling of neural development." European Organ-on-Chip Conference (EUROoC), Graz, Austria (07/2019). Poster presentation.

I. Matthiesen, T.E. Winkler, D. Voulgaris, P. Nikolakopoulou, and A. Herland. "Modeling of the human blood brain barrier (BBB) in stroke." SELECTBIO Organ-on-a-Chip & Tissue-on-a-Chip Europe, Rotterdam, The Netherlands (06/2018). Poster presentation.

D. Voulgaris, P. Nikolakopoulou, I. Matthiesen, T.E. Winkler, and A. Herland. "Human stem cell derived microglia in a Neurovascular model." Organs- and Tissues-on-Chips Keystone Symposium, Big Sky, Montana (04/2018). Poster Presentation.

R.C. Huiszoon, S. Subramanian, T.E. Winkler, S. Preza, and R. Ghodssi. "Experimental and theoretical analysis of biofilm formation and growth on cylindrical surfaces with impedimetric sensors." American Chemical Society (ACS) National Meeting, Washington, District of Columbia (08/2017). Oral presentation.

R.C. Huiszoon, S. Preza, P.R. Rajasekaran, T.E. Winkler, W.E. Bentley, and R. Ghodssi. "Electrodynamic modeling of bacterial biofilm impedance sensing." BMES/FDA Frontiers in Medical Devices Conference, Washington, District of Columbia (05/2017). Oral presentation.

S. Chu, B. Hurwitz, T.E. Winkler, A.D. Brown, J.N. Culver, and R. Ghodssi. "3D-EBP: A programmable 3D bionanoreceptor assembly." IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Las Vegas, Nevada (01/2017). Proceedings published. Oral presentation.

D.L. Kelly, E. Kim, T.E. Winkler, C. Kitchen, M. Kang, G.E. Banis, W.E. Bentley, R. Ghodssi, and G.F. Payne. "New Techniques for Oxidative Stress Measurement: Potential Biomarker and Outcome Measure in Schizophrenia." American College of Neuropsychopharmacology (ACNP) Annual Meeting, Hollywood, Florida (12/2016). Poster Presentation.

R. Huiszoon, S. Subramanian, T.E. Winkler, H.O. Sintim, W.E. Bentley, and R. Ghodssi. "Bacterial biofilms on 3D-printed implant materials." American Vacuum Society (AVS) International Symposium, Nashville, Tennessee (11/2016). Oral presentation.

G.E. Banis, P. Barton, T.E. Winkler, S.E. Chocron, E. Kim, H. Ben-Yoav, D. Kelly, G.F. Payne, and R. Ghodssi. "Impact of Protein Binding on Electrochemical Antipsychotic Monitoring." Materials Research Society (MRS) Spring Meeting, Phoenix, Arizona (03/2016). Oral presentation.

R. Dietrich, T.E. Winkler, H. Ben-Yoav, S.E. Chocron, E. Kim, D.L. Kelly, G.F. Payne, and R. Ghodssi. "The Interplay of Electrode Materials and Biomaterials in a Catechol-Modified Chitosan-Based Sensor for Clozapine Detection." American Vacuum Society (AVS) International Symposium, Baltimore, Maryland (11/2014). Oral presentation.

D.L. Kelly, H. Ben-Yoav, V. Stock, T.E. Winkler, G.F. Payne, S.E. Chocron, E. Kim, G. Vyas, R.C. Love, H.J. Wehring, K.M. Sullivan, S. Feldman, F. Liu, R.P. McMahon, R. Ghodssi. "Development of a lab-on-a-chip biosensor for clozapine monitoring." College of Psychiatric and Neurologic Pharmacists (CPNP) Annual Meeting, Phoenix, Arizona (04/2014). Poster presentation.

D.L. Kelly, H. Ben-Yoav, V. Stock, T.E. Winkler, G.F. Payne, S.E. Chocron, E. Kim, G. Vyas, R.C. Love, H.J. Wehring, K.M. Sullivan, S. Feldman, F. Liu, R.P. McMahon, R. Ghodssi. "Development of a lab-on-a-chip biosensor for clozapine monitoring." American College of Neuropsychopharmacology (ACNP) Annual Meeting, Hollywood, Florida (12/2013). Poster presentation.

H. Ben-Yoav, S.E. Chocron, T.E. Winkler, E. Kim, D.L. Kelly, G.F. Payne, and R. Ghodssi. "The effect of Vitamin C for point-of-care blood analysis applications using an electrochemical biosensor." IEEE Sensors Conference, Baltimore, Maryland (11/2013). Proceedings published. Oral presentation.

H. Ben-Yoav, T.E. Winkler, S.E. Chocron, G.R. Costa, S.M. Restaino, N. Woolsey, E. Kim, D.L. Kelly, G.F. Payne, and R. Ghodssi. "Towards Personalized Mental Healthcare: An Electrochemically-Amplified Biosensor for Clozapine Antipsychotic Treatment Monitoring." International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS), Freiburg, Germany (10/2013). Proceedings published. Poster presentation.

H. Ben-Yoav, T.E. Winkler, S.E. Chocron, S.M. Restaino, G.R. Costa, E. Kim, D.L. Kelly, G.F. Payne, and R. Ghodssi. "Bio-amplifying lab-on-a-chip for antipsychotic clozapine treatment monitoring." International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers & Eurosensors), Barcelona, Spain (06/2013). Proceedings published. Poster presentation.